Abstract
Background: The main challenge in radiation therapy (RT) has been the destruction of tumor or cancerous tissue while causing the least damage to healthy and normal tissues around the tumor. This is despite the fact that the maximum tolerated dose for normal tissue is limited, and this factor limits tumor destruction with radiation, thus lowering the efficiency of RT. The flash effect was initially proposed as a solution for the movement of the organ under treatment, such as the lung, demonstrating that tissue displacement occurs with breathing.
Methods: In this study, the feasibility of achieving the flash effect, in the direction of the beam and perpendicular to the direction of the radiation beam was investigated using X-rays with energies in keV.
Results: The results of this study, which is the only examination of the effect of distance on radiation, revealed that the amount of energy received in the target increased with the shortening of the distance, and on the other hand, in the direction perpendicular to the radiation, the extent and dispersion of the beam were reduced with the shortening of the distance between the source and the surface of the phantom.
Conclusion: This issue can justify in flash effect, the beam will be more concentrated and theside tissues will be less affected by the radiation compared to conventional radiation therapy