Background: Lipid peroxidation reaction and plasma malondialdehyde (MDA) production are important prognoses in the formation and development of neurodegenerative diseases. The link between lipid peroxidation reaction and plasma MDA in multiple sclerosis (MS) patients is poorly understood. In this study, the plasma MDA values of people with MS and normal people were measured.
Methods: In this study, 70 patients with MS and 70 thermally healthy individuals were selected. Their blood samples were poured into the buffer, and the plasma was separated. Then, plasma MDA values were measured through the thiobarbituric acid (TBA) method.
Results: The results showed that the values of plasma MDA in two groups of patients with MS and healthy people are 1.49±0.46 and 0.58±0.15 μmol/L, respectively.
Conclusion: The findings of this research revealed that the levels of plasma MDA in MS patients are higher than those in healthy people. Therefore, these patients exhibited elevated oxidative stress.